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KMID : 0371319940470020288
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Journal of the Korean Surgical Society
1994 Volume.47 No. 2 p.288 ~ p.295
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An Experience of Partial Live Transplantation for Congenital Biliary Atresia
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김수태
김건표/이건욱. 김상준/윤여규/윤효영/안문상/김우기/박귀원/조마해
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Abstract
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Liver transplantation has become the preferred treatment for the patients with end-stage liver disease. But orthotopic liver transplantation or the pediatric patients is often limited by the availability of size-matched donor organs. Use of
reduced-size
liver transplantation can increase available donors for pediatric patients.
In Korea. In July 11, 1992, a 11 month old boy with congenital biliaty atresia was treated with reduced-size orthotopic liver transplantation at Seoul National University Hospital for the first time. He was found to have deep jaundice and achohc
stool
after birth. At this age of 2 months, he underwent Kasai operation without complications. But his jaundice was not reheved and serum bilirubin was 10.0mg/dl in OPD follow up. On July 11, 1992, the reduced-size orthotopic liver transplantation was
completed successfully. IIIis diseased liver ws removed and replaced with the left lateral segment of the adult donor liver from a brain dead patient, using the technique similar to the living related segmental graft. The body weight ratio was
1:8.
The
biliary reconstruction was done using Roux-en Y choledochojejunostomy. Postoperatively, he was managed using standard protocols and immunosuppression was based on cyclosporine and steroids. No technical complication has occurred. Acute rejection
episode
was developed and treated with steroid. Minor complications were massive ascites, hypertension, and liver function test abnormalities. We report our first experience in reduced-size orthotopic liver transplantation in Korea.
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KEYWORD
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